Across TCGA cell cohorts, AARD RNA expression is significantly associated with the go_rna of many other GO terms, with 3,637 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible AARD-associated GO terms across cancer lineages are Mitochondrial electron transport, cytochrome c to oxygen, Regulation of protein modification by small protein conjugation or removal, and Cardiac muscle cell action potential. Each is linked with AARD in more than 8 cancer types. Because this analysis shows association rather than direction, both AARD-to-partner and partner-to-AARD results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AARD→partner) and Y-score (partner→AARD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Mitochondrial electron transport, cytochrome c to oxygen →	+0.065	+1.212	<.001	<.001	3	8
BLOOD_Leukemia	Regulation of protein modification by small protein conjugation or removal →	+0.032	+0.632	<.001	<.001	3	8
OVARY	Cardiac muscle cell action potential →	-0.125	-1.972	<.001	<.001	3	8
SKIN	Oxidative phosphorylation →	+0.086	+0.827	<.001	.008	3	8
BREAST	Action potential →	-0.087	-2.499	.002	.003	3	7
BLOOD_Leukemia	Regulation of post-translational protein modification →	+0.038	+1.070	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,637 associations by consensus.

Exploration

AARD survival (RNA) · tumor vs normal (RNA) · all AARD data types