AAMP

Across TCGA patient cohorts, AAMP protein abundance is significantly associated with the RNA expression of many other genes, with 11,011 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AAMP-associated genes across cancer lineages are ECM2, FARSB, and ATIC. Each is linked with AAMP in more than 4 cancer types. Because this analysis shows association rather than direction, both AAMP-to-partner and partner-to-AAMP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AAMP versus ECM2 in BRCA, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AAMP→partner) and Y-score (partner→AAMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ECM2 →	-1.028	-0.295	<.001	.001	3	5
LSCC	FARSB →	+0.512	+0.394	<.001	<.001	3	5
HNSC	ATIC →	+0.828	+0.316	<.001	<.001	3	5
HNSC	CNOT9 →	+0.684	+0.369	.001	<.001	3	5
UCEC	RBMS3 →	-0.732	-0.298	<.001	.001	3	5
UCEC	MAIP1 →	+0.646	+0.338	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,011 associations by consensus.

AAMP vs ECM2 — BRCA

Explore this scatter interactively →