AAMP

Across TCGA cell cohorts, AAMP RNA expression is significantly associated with the go_rna of many other GO terms, with 2,542 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AAMP-associated GO terms across cancer lineages are Protein-RNA covalent cross-linking repair, Spliceosomal tri-snRNP complex assembly, and Axo-dendritic transport. Each is linked with AAMP in more than 13 cancer types. Because this analysis shows association rather than direction, both AAMP-to-partner and partner-to-AAMP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-RNA covalent cross-linking repair grouped by AAMP-low versus AAMP-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AAMP→partner) and Y-score (partner→AAMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Protein-RNA covalent cross-linking repair →	+0.117	+0.575	<.001	<.001	3	14
BREAST	Spliceosomal tri-snRNP complex assembly →	+0.083	+0.491	<.001	.005	3	9
BLOOD_Lymphoma	Axo-dendritic transport →	+0.041	+0.683	.002	.001	3	8
BREAST	DNA replication-dependent chromatin disassembly →	+0.074	+0.424	.001	.002	3	8
LUNG_NSCLC_LUSC	COP9 signalosome assembly →	+0.126	+0.513	.003	.003	3	8
BLOOD_Leukemia	Transport along microtubule →	+0.028	+0.479	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,542 associations by consensus.

Protein-RNA covalent cross-linking repair by AAMP expression — OVARY

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