AADAC

Across TCGA patient cohorts, AADAC protein abundance is significantly associated with the RNA expression of many other genes, with 16,966 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AADAC-associated genes across cancer lineages are ADD3, RN7SL8P, and GPHA2. Each is linked with AADAC in more than 2 cancer types. Because this analysis shows association rather than direction, both AADAC-to-partner and partner-to-AADAC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AADAC versus ADD3 in HNSC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AADAC→partner) and Y-score (partner→AADAC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ADD3 →	+0.844	+0.990	<.001	.001	3	3
LUAD	RN7SL8P →	+0.771	+0.681	.001	.005	3	3
PDAC	GPHA2 →	+0.880	+0.750	.002	.001	3	2
HNSC	TRIOBP →	+0.609	+0.825	<.001	<.001	3	2
HNSC	BIK →	+1.250	+0.917	<.001	.001	3	2
HNSC	ALDH3A1 →	+2.323	+1.113	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,966 associations by consensus.

AADAC vs ADD3 — HNSC

Explore this scatter interactively →