AAAS

Across TCGA patient cohorts, AAAS RNA expression is significantly associated with the protein abundance of many other proteins, with 13,593 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AAAS-associated proteins across cancer lineages are SART3, MYG1, and TFCP2. Each is linked with AAAS in more than 5 cancer types. Because this analysis shows association rather than direction, both AAAS-to-partner and partner-to-AAAS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AAAS versus SART3 in GBM, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AAAS→partner) and Y-score (partner→AAAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SART3 →	+0.246	+0.288	.001	<.001	3	6
OV	MYG1 →	+0.333	+0.366	<.001	<.001	3	6
LSCC	TFCP2 →	+0.321	+0.474	<.001	<.001	3	5
LSCC	SCAF11 →	+0.221	+0.347	<.001	<.001	3	5
GBM	SNRPD2 →	+0.182	+0.152	.001	.007	3	5
LSCC	DDX47 →	+0.357	+0.415	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,593 associations by consensus.

AAAS vs SART3 — GBM

Explore this scatter interactively →