A4GNT

Across TCGA pan-cancer cohorts, A4GNT Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated A4GNT data layer compared with 19 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher A4GNT Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated A4GNT expression acts as an unfavorable survival marker.

KIRC, COAD, and HNSC are the cancer types where A4GNT Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.062	0.874	<.001	36	view →
COAD	OS	Median	All	0.172	0.870	<.001	14	view →
HNSC	DFS	Median	II,III,IV	0.208	0.685	.043	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

A4GNT–KIRC (OS)

Open the KIRC breakdown →