A4GNT

Across TCGA patient cohorts, A4GNT mutation is significantly associated with the RNA expression of many other genes, with 1,419 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible A4GNT-associated genes across cancer lineages are RNU6-764P, SUMO2P7, and NFYAP1. Each is linked with A4GNT in more than 2 cancer types. Because this analysis shows association rather than direction, both A4GNT-to-partner and partner-to-A4GNT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-764P grouped by A4GNT-low versus A4GNT-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (A4GNT→partner) and Y-score (partner→A4GNT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-764P →	+0.122	+4.748	<.001	.003	3	3
SKCM	SUMO2P7 →	+0.178	+3.032	.003	.009	3	3
CESC	NFYAP1 →	+0.214	+5.595	<.001	<.001	3	2
CESC	CTBP2P10 →	+0.029	+5.837	<.001	.001	3	2
LUAD	NUDT4B →	+0.088	+2.868	<.001	.009	3	2
LUAD	SEPTIN14P5 →	+0.036	+4.523	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,419 associations by consensus.

RNU6-764P by A4GNT expression — LUAD

Explore this box plot interactively →