A4GNT

Across TCGA patient cohorts, A4GNT mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible A4GNT-associated genes across cancer lineages are STAT3_pY705, TFRC, and ASNS. Each is linked with A4GNT in more than 2 cancer types. Because this analysis shows association rather than direction, both A4GNT-to-partner and partner-to-A4GNT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STAT3_pY705 grouped by A4GNT-low versus A4GNT-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (A4GNT→partner) and Y-score (partner→A4GNT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.387	-2.000	.001	.032	3	3
UCEC	TFRC →	+0.720	+2.700	.002	.006	3	2
UCEC	ASNS →	+0.542	+3.169	<.001	.018	3	2
LUAD	RAD51 →	+0.278	+2.824	.008	.036	3	1
UCEC	EGFR →	-0.145	-2.000	.044	.032	3	1
UCEC	A-Raf_pS299 →	-0.168	-3.459	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

STAT3_pY705 by A4GNT expression — UCEC

Explore this box plot interactively →