A4GNT

Across TCGA cell cohorts, A4GNT RNA expression is significantly associated with the go_rna of many other GO terms, with 1,689 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible A4GNT-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Golgi vesicle transport, and Actin polymerization-dependent cell motility. Each is linked with A4GNT in more than 7 cancer types. Because this analysis shows association rather than direction, both A4GNT-to-partner and partner-to-A4GNT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by A4GNT-low versus A4GNT-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (A4GNT→partner) and Y-score (partner→A4GNT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.112	+0.142	.001	.007	3	7
SKIN	Golgi vesicle transport →	+0.039	+0.082	.001	.006	3	7
LUNG_SCLC	Actin polymerization-dependent cell motility →	+0.125	+0.094	<.001	.002	2	8
LUNG_NSCLC_LUSC	Protein targeting to lysosome involved in chaperone-mediated autophagy →	+0.159	+0.120	.002	.006	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.072	+0.082	.001	.006	3	6
UPPER_AERODIGESTIVE_TRACT	Immunological synapse formation →	+0.080	+0.084	.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,689 associations by consensus.

Negative regulation of myoblast fusion by A4GNT expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →