A4GNT

Across TCGA cell cohorts, A4GNT mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible A4GNT-associated genes across cancer lineages are GKN2 and OR10W1. Each is linked with A4GNT in more than 1 cancer types. Because this analysis shows association rather than direction, both A4GNT-to-partner and partner-to-A4GNT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GKN2 grouped by A4GNT-low versus A4GNT-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (A4GNT→partner) and Y-score (partner→A4GNT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	GKN2 →	+0.372	+4.017	.004	.007	3	1
LARGE_INTESTINE	OR10W1 →	+0.019	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GKN2 by A4GNT expression — OESOPHAGUS

Explore this box plot interactively →