A2ML1-AS1

Across TCGA pan-cancer cohorts, A2ML1-AS1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of A2ML1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where A2ML1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types A2ML1-AS1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

UCEC and KICH are the cancer types where A2ML1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in A2ML1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	+0.146	.004	4	view →
KICH	All	All	−0.041	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

A2ML1-AS1–UCEC

Open the UCEC breakdown →