A1CF

Across TCGA patient cohorts, A1CF RNA expression is significantly associated with the protein abundance of many other proteins, with 8,114 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible A1CF-associated proteins across cancer lineages are ICAM1, CEP170B_S1513, and ERRFI1_S251. Each is linked with A1CF in more than 3 cancer types. Because this analysis shows association rather than direction, both A1CF-to-partner and partner-to-A1CF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, A1CF versus ICAM1 in PDAC, with a Pearson correlation of -0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (A1CF→partner) and Y-score (partner→A1CF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ICAM1 →	-0.467	-0.624	<.001	.002	3	4
PDAC	CEP170B_S1513 →	-0.582	-0.726	.002	.001	3	3
PDAC	ERRFI1_S251 →	-0.656	-0.891	<.001	<.001	3	3
UCEC	NAXE →	+0.325	+0.598	<.001	<.001	3	3
UCEC	PDZK1 →	+1.068	+0.636	.001	.004	3	3
CCRCC	AFDN →	+0.248	+1.591	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,114 associations by consensus.

A1CF vs ICAM1 — PDAC

Explore this scatter interactively →