A1BG

Across TCGA patient cohorts, A1BG protein abundance is significantly associated with the RNA expression of many other genes, with 14,380 significant associations in total. GBM shows the largest number of these associations.

The most reproducible A1BG-associated genes across cancer lineages are COLEC12, LINC00702, and GPIHBP1. Each is linked with A1BG in more than 6 cancer types. Because this analysis shows association rather than direction, both A1BG-to-partner and partner-to-A1BG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, A1BG versus COLEC12 in BRCA, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (A1BG→partner) and Y-score (partner→A1BG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	COLEC12 →	+1.033	+0.344	<.001	<.001	3	7
CCRCC	LINC00702 →	+0.643	+0.577	<.001	<.001	3	7
CCRCC	GPIHBP1 →	+1.097	+0.511	<.001	<.001	3	7
CCRCC	DIPK2B →	+0.738	+0.497	<.001	<.001	3	7
OV	ADGRF5 →	+0.905	+0.563	.002	.003	3	7
GBM	LYVE1 →	+1.199	+0.377	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,380 associations by consensus.

A1BG vs COLEC12 — BRCA

Explore this scatter interactively →