A1BG-AS1

Across TCGA pan-cancer cohorts, A1BG-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of A1BG-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where A1BG-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types A1BG-AS1 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.

COAD, HNSC, and BRCA are the cancer types where A1BG-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in A1BG-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	−0.317	<.001	10	view →
HNSC	All	III,IV	+0.566	<.001	9	view →
BRCA	All	All	+0.305	<.001	6	view →
KICH	Female	All	−0.713	<.001	5	view →
LUSC	All	All	−0.414	<.001	5	view →
THCA	All	All	+0.358	<.001	4	view →
CHOL	All	II,III,IV	−1.130	.021	3	view →
LUAD	All	All	−0.319	<.001	3	view →
UCEC	All	All	−0.632	.004	2	view →
PRAD	All	All	−0.562	<.001	2	view →
KIRC	Male	All	+0.211	.006	2	view →
LIHC	Male	II,III,IV	−0.519	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

A1BG-AS1–COAD

Open the COAD breakdown →