Positive regulation of vasculogenesis

Across TCGA cell cohorts, RNA activity of the Positive regulation of vasculogenesis pathway is significantly associated with the RNA expression of multiple genes, with the LIVER cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are MYG1, ASNSD1, and TIMM22, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Positive regulation of vasculogenesis activity versus MYG1 in LIVER (Pearson r = -0.68).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	MYG1 →	-1.042	-1.527	<.001	.008	3	4
URINARY_TRACT	ASNSD1 →	-1.085	-1.454	.003	.005	3	4
URINARY_TRACT	TIMM22 →	-0.590	-0.849	.006	.009	3	4
URINARY_TRACT	TSN →	-0.421	-1.204	.003	.009	3	4
LUNG_SCLC	FGD1 →	-0.819	-0.824	.001	.002	3	4
LUNG_SCLC	DLX1 →	-2.554	-1.288	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:2001214 vs MYG1 — LIVER

Explore this scatter interactively →