Neutrophil migration

Across TCGA cell cohorts, RNA activity of the Neutrophil migration pathway is significantly associated with the RNA expression of multiple genes, with the PANCREAS cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are ATPSCKMT, EEF1B2, and KIAA2013, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The box plot shows the strongest association, ATPSCKMT grouped by Neutrophil migration-low versus -high activity in PANCREAS.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	ATPSCKMT →	-0.673	-1.064	.004	.001	3	4
CNS	EEF1B2 →	+0.607	+0.776	.001	.005	3	3
CNS	KIAA2013 →	-0.746	-0.828	.007	.004	3	3
CNS	ATP5IF1 →	-0.618	-0.926	<.001	<.001	3	3
CNS	RPS3 →	+1.027	+1.062	.003	<.001	3	3
CNS	SLC43A2 →	-1.315	-0.997	.003	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

ATPSCKMT by Neutrophil migration activity — PANCREAS

Explore this box plot interactively →