Glycosyl compound metabolic process

pathway activity — cross-omics
GO:1901657Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Glycosyl compound metabolic process pathway is significantly associated with the protein abundance of multiple proteins, with the LUAD cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are AKR1C2, RPL24, and SNIP1_S76, each associated with the pathway in up to 6 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADAKR1C2 →+1.502+0.025.001.00736
OVRPL24 →-0.459-0.017<.001.00835
LUADSNIP1_S76 →-0.632-0.026.001<.00135
HNSCEEF2_S502 →-0.597-0.046.001.00526
LUADABLIM1_S426 →+0.616+0.029.001<.00135
LUADPRPF4B_S294 →-0.545-0.029.006<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration