Acetate ester transport

pathway activity — cross-omics
GO:1901374Cross-omicsRNA → PROTEIN-MSCellPairwise association · TCGA cohorts

Across TCGA cell cohorts, RNA activity of the Acetate ester transport pathway is significantly associated with the protein abundance of multiple proteins, with the BLOOD_Lymphoma cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are MVP, PLEC, and RBM14, each associated with the pathway in up to 7 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Acetate ester transport activity versus MVP in BLOOD_Lymphoma (Pearson r = 0.40).

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaMVP →+1.923+0.601<.001.00527
BLOOD_LymphomaPLEC →+2.050+1.012<.001.00536
CNSRBM14 →-0.675-1.007<.001.00136
BLOOD_LeukemiaRAB27A →+1.892+0.932<.001<.00136
BLOOD_LeukemiaZYX →+3.244+0.890<.001<.00135
BLOOD_LeukemiaABHD11 →+0.886+0.857.003.00435
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:1901374 vs MVP — BLOOD_Lymphoma

Per-sample scatter of Acetate ester transport activity vs MVP in BLOOD_Lymphoma.

Explore this scatter interactively →

Exploration