Across TCGA patient cohorts, RNA activity of the Reactive gliosis pathway is significantly associated with the protein abundance of multiple proteins, with the GBM cohort showing a particularly strong set of associations.
The most reproducible pathway-associated proteins across cancer lineages are OTUD4_S893, PRPF4B_S368, and UBE2L6, each associated with the pathway in up to 6 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.
Each partner is linked to its corresponding Q-omics profile.