Dendritic transport of ribonucleoprotein complex

pathway activity — cross-omics
GO:0098961Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Dendritic transport of ribonucleoprotein complex pathway is significantly associated with the protein abundance of multiple proteins, with the OV cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are PURA, OXR1, and BAZ1B_S1342, each associated with the pathway in up to 8 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVPURA →+0.458+0.055.001.00138
GBMOXR1 →+0.420+0.062<.001<.00137
LUADBAZ1B_S1342 →-0.571-0.061<.001.00236
LUADH1-10_S31 →-0.994-0.087<.001<.00136
PDACRSL1D1 →-0.382-0.053<.001<.00135
PDACSRRM1_S583 →-0.472-0.042<.001.00135
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration