Anterograde axonal transport of mitochondrion

pathway activity — cross-omics
GO:0098957Cross-omicsRNA → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Anterograde axonal transport of mitochondrion pathway is significantly associated with the RNA expression of multiple genes, with the CHOL cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are AGTPBP1, TGFBR1, and FEZ1, each associated with the pathway in up to 27 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CHOLAGTPBP1 →+0.991+0.083.007.009127
UVMTGFBR1 →+1.141+0.055<.001<.001323
DLBCFEZ1 →+1.888+0.103<.001<.001322
UVMNIN →+0.909+0.051<.001<.001322
THYMSEPTIN11 →+1.264+0.067<.001<.001322
UVMPEAK1 →+0.711+0.055<.001<.001322
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration