Dendritic transport

Across TCGA patient cohorts, RNA activity of the Dendritic transport pathway is significantly associated with the protein abundance of multiple proteins, with the COAD cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are STAU2, LYAR, and RPL5_S185, each associated with the pathway in up to 7 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Dendritic transport activity versus STAU2 in COAD (Pearson r = 0.09).

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	STAU2 →	+0.260	+0.036	.002	.001	3	7
GBM	LYAR →	-0.338	-0.110	.001	<.001	3	7
HNSC	RPL5_S185 →	-0.544	-0.084	<.001	<.001	3	6
LUAD	DDX21_S89 →	-1.004	-0.077	<.001	<.001	3	6
HNSC	EEF2_T435 →	-0.657	-0.091	<.001	<.001	3	6
LUAD	NFKB2_S222 →	-0.594	-0.055	<.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0098935 vs STAU2 — COAD

Explore this scatter interactively →