Dendritic transport

Across TCGA cell cohorts, RNA activity of the Dendritic transport pathway is significantly associated with the RNA expression of multiple genes, with the BLOOD_Lymphoma cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are FLOT2, STAU1, and AIG1, each associated with the pathway in up to 8 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Dendritic transport activity versus FLOT2 in BLOOD_Lymphoma (Pearson r = 0.41).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	FLOT2 →	+1.367	+0.204	<.001	.007	2	8
OESOPHAGUS	STAU1 →	+0.879	+0.277	<.001	.001	3	6
BLOOD_Leukemia	AIG1 →	+2.376	+0.114	<.001	.006	3	5
LUNG_SCLC	CHST14 →	+1.283	+0.202	<.001	.006	3	5
BLOOD_Lymphoma	ADD1 →	+0.875	+0.210	<.001	<.001	3	4
STOMACH	TNFAIP1 →	+0.765	+0.150	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0098935 vs FLOT2 — BLOOD_Lymphoma

Explore this scatter interactively →