Receptor localization to non-motile cilium

Across TCGA patient cohorts, RNA activity of the Receptor localization to non-motile cilium pathway is significantly associated with the RNA expression of multiple genes, with the UVM cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are BBIP1, TUB, and SENP7, each associated with the pathway in up to 29 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Receptor localization to non-motile cilium activity versus BBIP1 in UVM (Pearson r = 0.33).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	BBIP1 →	+0.779	+0.069	<.001	<.001	3	29
THYM	TUB →	+2.020	+0.099	<.001	<.001	3	24
UVM	SENP7 →	+1.158	+0.065	<.001	<.001	3	23
UVM	TIAL1 →	+0.924	+0.074	<.001	<.001	3	23
UVM	MICU3 →	+1.504	+0.074	<.001	<.001	3	23
UVM	NIFK-AS1 →	+0.591	+0.044	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0097500 vs BBIP1 — UVM

Explore this scatter interactively →