Neuroblast migration

pathway activity — cross-omics
GO:0097402Cross-omicsRNA → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Neuroblast migration pathway is significantly associated with the RNA expression of multiple genes, with the SKCM cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are EDNRB, FUT10, and FLT1, each associated with the pathway in up to 25 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMEDNRB →+1.719+0.084<.001<.001325
LAMLFUT10 →+0.766+0.252<.001<.001321
THYMFLT1 →+1.333+0.101<.001<.001318
KICHACBD5 →+0.851+0.064.009.005119
THYMC6orf89 →+0.699+0.089<.001<.001317
LIHCSARAF →+0.508+0.042<.001<.001316
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration