Renal albumin absorption

pathway activity — cross-omics
GO:0097018Cross-omicsRNA → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Renal albumin absorption pathway is significantly associated with the RNA expression of multiple genes, with the THYM cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are EDNRA, COL4A2, and EDNRB, each associated with the pathway in up to 29 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
THYMEDNRA →+2.429+0.110<.001<.001329
MESOCOL4A2 →+1.902+0.079<.001<.001327
PRADEDNRB →+1.745+0.129<.001<.001327
MESOCOL4A1 →+2.191+0.079<.001<.001327
THYMOLFML1 →+1.753+0.067<.001<.001327
PCPGENG →+1.124+0.072<.001<.001326
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration