Eosinophil migration

Across TCGA patient cohorts, RNA activity of the Eosinophil migration pathway is significantly associated with the RNA expression of multiple genes, with the CCRCC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are SELE, TMOD1, and MMRN1, each associated with the pathway in up to 3 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Eosinophil migration activity versus SELE in CCRCC (Pearson r = 0.13).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SELE →	+0.717	+0.624	.006	.001	3	3
PDAC	TMOD1 →	+0.575	+0.440	.001	.004	3	3
PDAC	MMRN1 →	+0.577	+0.334	.001	.005	3	3
PDAC	HMGCLL1 →	+0.555	+0.457	.004	.001	3	3
PDAC	RAB3C →	+0.514	+0.346	<.001	.004	3	3
LUAD	GPR171 →	+0.917	+0.471	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0072677 vs SELE — CCRCC

Explore this scatter interactively →