Ureter morphogenesis

pathway activity — cross-omics
GO:0072197Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Ureter morphogenesis pathway is significantly associated with the protein abundance of multiple proteins, with the LUAD cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are SOX8, EIF3A_S881, and SPEN_S1278, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADSOX8 →+1.556+0.457<.001<.00134
OVEIF3A_S881 →-0.716-0.293.006<.00134
HNSCSPEN_S1278 →-0.569-0.683.001.00133
LSCCABR_T74 →-0.726-0.858<.001<.00133
LUADPPP1R37_S561 →-0.778-0.561<.001<.00133
LSCCPTGES3_S148 →+0.680+0.441.002.00424
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration