Nephric duct morphogenesis

pathway activity — cross-omics
GO:0072178Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Nephric duct morphogenesis pathway is significantly associated with the RNA expression of multiple genes, with the BRCA cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are NUDT12, TBX2-AS1, and CGAS, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCANUDT12 →+0.767+0.655.009.00135
BRCATBX2-AS1 →+0.660+0.508.003.00435
CCRCCCGAS →-0.309-0.130<.001.00135
LUADIGKV1-9 →-1.296-0.176<.001.00135
OVKBTBD11 →+1.167+0.238<.001.00625
PDACGRM8 →+0.315+0.584.002.00534
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration