Renal vesicle formation

Across TCGA cell cohorts, RNA activity of the Renal vesicle formation pathway is significantly associated with the RNA expression of multiple genes, with the BREAST cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are RB1, RCBTB1, and ADIPOR2, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The box plot shows the strongest association, RB1 grouped by Renal vesicle formation-low versus -high activity in BREAST.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	RB1 →	-1.551	-1.404	.002	<.001	3	4
LUNG_NSCLC_LUAD	RCBTB1 →	-0.710	-1.028	.009	.002	3	4
OVARY	ADIPOR2 →	-1.045	-1.879	.008	<.001	3	4
LARGE_INTESTINE	LRRC19 →	-0.716	-0.741	.009	.003	3	3
BLOOD_Leukemia	ARSK →	+0.734	+0.331	.003	.002	3	3
PANCREAS	TLNRD1 →	-0.718	-1.459	.006	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

RB1 by Renal vesicle formation activity — BREAST

Explore this box plot interactively →