Fat cell proliferation

Across TCGA patient cohorts, RNA activity of the Fat cell proliferation pathway is significantly associated with the RNA expression of multiple genes, with the OV cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are LNCTAM34A, CNPY2, and ID1, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Fat cell proliferation activity versus LNCTAM34A in OV (Pearson r = 0.13).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LNCTAM34A →	+0.363	+0.518	.006	.009	3	5
PDAC	CNPY2 →	+0.174	+0.461	.003	.001	3	4
HNSC	ID1 →	-1.060	-0.926	.004	<.001	3	4
LSCC	LINC01232 →	+0.723	+0.648	<.001	.005	3	4
CCRCC	EPHA4 →	-0.840	-0.987	.001	.001	3	4
LUAD	CENPL →	+0.516	+0.762	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0070341 vs LNCTAM34A — OV

Explore this scatter interactively →