Stomach development

pathway activity — cross-omics
GO:0062094Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Stomach development pathway is significantly associated with the protein abundance of multiple proteins, with the OV cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are KCNQ1_S27, PGP, and SEPTIN4_S325, each associated with the pathway in up to 6 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVKCNQ1_S27 →+0.821+0.059.001<.00136
CCRCCPGP →-0.219-0.059.003.00135
CCRCCSEPTIN4_S325 →+0.466+0.060<.001<.00134
CCRCCTLN1_S2040 →+0.677+0.070<.001<.00134
CCRCCVCL_S346 →+0.563+0.070<.001<.00134
OVCNOT11 →-0.209-0.053.004.00734
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration