Motor behavior

Across TCGA cell cohorts, RNA activity of the Motor behavior pathway is significantly associated with the RNA expression of multiple genes, with the BLOOD_Lymphoma cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are UBL7, ZNF689, and ZNF746, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Motor behavior activity versus UBL7 in BLOOD_Lymphoma (Pearson r = 0.46).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	UBL7 →	+0.732	+1.057	.008	<.001	3	5
BLOOD_Lymphoma	ZNF689 →	+0.710	+1.057	.001	.002	3	5
BLOOD_Lymphoma	ZNF746 →	+0.683	+1.111	.003	<.001	3	5
BLOOD_Leukemia	ADAM22 →	+1.226	+1.089	.001	<.001	3	5
BLOOD_Leukemia	CAMK4 →	+2.642	+1.009	<.001	<.001	3	5
BLOOD_Lymphoma	TOLLIP →	+0.689	+0.983	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0061744 vs UBL7 — BLOOD_Lymphoma

Explore this scatter interactively →