Oviduct development

pathway activity — cross-omics
GO:0060066Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Oviduct development pathway is significantly associated with the protein abundance of multiple proteins, with the GBM cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are APBB1IP, ARHGAP45, and GPSM3, each associated with the pathway in up to 8 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMAPBB1IP →+0.631+0.126<.001<.00138
GBMARHGAP45 →+0.487+0.077<.001<.00136
GBMGPSM3 →+0.692+0.126<.001<.00136
GBMSTAB1 →+0.642+0.123<.001<.00135
GBMUBA7 →+0.368+0.070<.001<.00135
BRCAVAPB →-0.356-0.058<.001.00235
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration