Oviduct development

pathway activity — cross-omics
GO:0060066Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Oviduct development pathway is significantly associated with the RNA expression of multiple genes, with the LUAD cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are PIK3C2G, ID4, and KBTBD11, each associated with the pathway in up to 3 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADPIK3C2G →+1.184+0.105<.001.00733
LUADID4 →+0.628+0.099.004.00733
LUADKBTBD11 →+0.874+0.102<.001.00433
PDACRNU4-78P →+0.604+0.124.001<.00133
PDACGAN →+0.294+0.064.002.00933
HNSCCTNND1 →+0.484+0.098.001.00433
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

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