Positive regulation of protein glycosylation

pathway activity — cross-omics
GO:0060050Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Positive regulation of protein glycosylation pathway is significantly associated with the RNA expression of multiple genes, with the OV cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are TCEAL1, RERG, and HSD17B4, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVTCEAL1 →-0.494-0.520.002.00934
OVRERG →-1.229-0.570.008.00733
PDACHSD17B4 →-0.242-0.434.003.00233
PDACTNFAIP8L2 →-0.369-0.386.003.00833
GBMTDRD6 →-0.469-0.186.002.00233
UCECARMCX1 →-0.846-0.657<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration