Monoacylglycerol catabolic process

Across TCGA cell cohorts, RNA activity of the Monoacylglycerol catabolic process pathway is significantly associated with the RNA expression of multiple genes, with the OVARY cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are POLR2H, RMND5A, and FANK1, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Monoacylglycerol catabolic process activity versus POLR2H in OVARY (Pearson r = -0.54).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	POLR2H →	-0.948	-1.257	.002	.004	3	4
LUNG_SCLC	RMND5A →	-0.644	-0.977	.007	.001	3	4
LIVER	FANK1 →	+2.311	+1.390	<.001	<.001	3	4
LIVER	EIF4B →	-0.985	-1.188	.003	.009	2	5
CNS	ABHD12 →	+0.867	+1.044	<.001	<.001	3	4
OVARY	DTD2 →	-1.011	-1.612	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0052651 vs POLR2H — OVARY

Explore this scatter interactively →