Myoblast proliferation

Across TCGA patient cohorts, RNA activity of the Myoblast proliferation pathway is significantly associated with the RNA expression of multiple genes, with the ACC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are MALAT1, CDK5, and IMMP1LP1, each associated with the pathway in up to 19 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Myoblast proliferation activity versus MALAT1 in ACC (Pearson r = -0.26).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	MALAT1 →	+0.699	+0.029	.005	.001	1	19
TGCT	CDK5 →	-0.572	-0.055	<.001	<.001	3	15
ESCA	IMMP1LP1 →	+0.346	+0.038	.009	.009	1	17
LAML	BACH1-IT2 →	+0.636	+0.065	.004	<.001	3	15
BLCA	SOX15 →	+2.256	+0.043	<.001	<.001	3	15
DLBC	ZFP36 →	+0.920	+0.039	.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0051450 vs MALAT1 — ACC

Explore this scatter interactively →