Myoblast proliferation

Across TCGA patient cohorts, RNA activity of the Myoblast proliferation pathway is significantly associated with the RNA expression of multiple genes, with the HNSC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are YEATS2, KLK7, and LINC00173, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Myoblast proliferation activity versus YEATS2 in HNSC (Pearson r = 0.04).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	YEATS2 →	+0.350	+0.159	.006	.007	3	3
HNSC	KLK7 →	-1.422	-0.156	.006	.007	3	3
BRCA	LINC00173 →	+1.015	+0.238	.003	.001	3	3
GBM	CEP192 →	+0.315	+0.740	.009	.004	3	3
GBM	INTS2 →	+0.315	+0.750	.002	.004	3	3
GBM	DCAF1 →	+0.227	+0.693	.002	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0051450 vs YEATS2 — HNSC

Explore this scatter interactively →