Sensory perception of taste

Across TCGA cell cohorts, RNA activity of the Sensory perception of taste pathway is significantly associated with the RNA expression of multiple genes, with the OVARY cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are DLST, MUTYH, and SUSD6, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The box plot shows the strongest association, DLST grouped by Sensory perception of taste-low versus -high activity in OVARY.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	DLST →	+0.434	+1.051	.003	<.001	3	5
STOMACH	MUTYH →	+0.819	+1.146	.003	.002	3	4
URINARY_TRACT	SUSD6 →	-1.332	-1.695	.001	.007	2	5
OVARY	PSMB6 →	+0.671	+1.186	<.001	<.001	3	4
OESOPHAGUS	NUP85 →	+0.725	+1.393	.007	.002	3	4
OESOPHAGUS	PRR11 →	+1.068	+1.097	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

DLST by Sensory perception of taste activity — OVARY

Explore this box plot interactively →