Across TCGA patient cohorts, RNA activity of the Paraxial mesoderm formation pathway is significantly associated with the protein abundance of multiple proteins, with the OV cohort showing a particularly strong set of associations.
The most reproducible pathway-associated proteins across cancer lineages are AUP1_S288, WDR46_S41, and CRACDL_S490, each associated with the pathway in up to 3 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.
Each partner is linked to its corresponding Q-omics profile.