Transport of virus

Across TCGA patient cohorts, RNA activity of the Transport of virus pathway is significantly associated with the protein abundance of multiple proteins, with the UCEC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are EHD1, SIRT6_S330, and SLC9A7_S693, each associated with the pathway in up to 6 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Transport of virus activity versus EHD1 in UCEC (Pearson r = -0.07).

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EHD1 →	+0.228	+0.051	.001	.002	3	6
COAD	SIRT6_S330 →	-0.259	-0.024	.004	.001	3	5
COAD	SLC9A7_S693 →	+0.851	+0.050	.001	.008	3	5
LUAD	SRSF11_S449 →	-1.837	-0.062	<.001	<.001	3	5
UCEC	TLN1 →	+0.343	+0.051	<.001	.002	3	5
COAD	VAT1 →	+0.284	+0.025	.003	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0046794 vs EHD1 — UCEC

Explore this scatter interactively →