Glucose import

pathway activity — cross-omics
GO:0046323Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Glucose import pathway is significantly associated with the protein abundance of multiple proteins, with the BRCA cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are CSRP1, LMCD1, and RSU1, each associated with the pathway in up to 7 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCACSRP1 →+0.561+0.042<.001<.00137
BRCALMCD1 →+0.632+0.045<.001<.00137
BRCARSU1 →+0.379+0.036<.001<.00136
OVSEPTIN4 →+0.566+0.036<.001<.00136
BRCATLN2 →+0.545+0.034<.001<.00136
BRCATLN2_T1843 →+0.449+0.024<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration