Hair cycle phase

pathway activity — cross-omics
GO:0044851Cross-omicsRNA → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Hair cycle phase pathway is significantly associated with the RNA expression of multiple genes, with the BLCA cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are WNT5A, WNT5A-AS1, and FERMT1, each associated with the pathway in up to 22 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAWNT5A →+1.533+0.078<.001<.001322
THYMWNT5A-AS1 →+1.257+0.076<.001<.001220
CHOLFERMT1 →+3.029+0.100<.001.003317
THYMSEPTIN1 →-1.071-0.059<.001<.001317
TGCTSERINC5 →+0.763+0.040<.001<.001217
THYMCTNNB1 →+1.065+0.082<.001<.001316
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration