Hair cycle phase

pathway activity — cross-omics
GO:0044851Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Hair cycle phase pathway is significantly associated with the protein abundance of multiple proteins, with the UCEC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are CTNNB1, TRIM29, and VSNL1, each associated with the pathway in up to 6 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCTNNB1 →+0.416+0.120<.001<.00136
BRCATRIM29 →+0.978+0.060<.001.00135
UCECVSNL1 →+1.682+0.172<.001<.00135
COADBTK →-0.536-0.057.009.00235
BRCALAD1 →+0.656+0.076<.001<.00135
LSCCNCKAP1L →-0.288-0.099.006<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration