Obsolete late nucleophagy

pathway activity — cross-omics
GO:0044805Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Obsolete late nucleophagy pathway is significantly associated with the RNA expression of multiple genes, with the CCRCC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are RNU6-377P, ARNILA, and C5orf63, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCRNU6-377P →-0.560-0.570.001.00234
LUADARNILA →-0.328-0.569.003.00125
HNSCC5orf63 →-0.432-0.596.008.00934
BRCAKPNA3 →-0.441-0.200.004.00134
GBMDISC1 →-0.585-0.240.002<.00134
LSCCVWA8 →-0.303-0.707.008.00133
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration