Induction of bacterial agglutination

Across TCGA patient cohorts, RNA activity of the Induction of bacterial agglutination pathway is significantly associated with the RNA expression of multiple genes, with the GBM cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are FCAR, IL6, and TREM1, each associated with the pathway in up to 7 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Induction of bacterial agglutination activity versus FCAR in GBM (Pearson r = 0.29).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FCAR →	+0.870	+0.617	<.001	.002	3	7
GBM	IL6 →	+1.542	+0.752	.001	.001	2	7
GBM	TREM1 →	+1.587	+0.681	<.001	.001	3	6
GBM	CXCR1 →	+1.042	+0.532	<.001	.005	3	6
GBM	CEACAM3 →	+0.544	+0.621	.003	.004	3	6
GBM	LILRA5 →	+1.148	+0.803	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0043152 vs FCAR — GBM

Explore this scatter interactively →