NAD transport

pathway activity — cross-omics
GO:0043132Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the NAD transport pathway is significantly associated with the RNA expression of multiple genes, with the LUAD cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are EBI3, CXCR3, and FAM32BP, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADEBI3 →+0.492+0.136<.001<.00134
LSCCCXCR3 →+0.980+0.575<.001<.00134
LUADFAM32BP →+0.559+0.156.004.00734
LUADPRKAR1B-AS1 →+0.397+0.166.006.00234
LUADPAG1 →+0.680+0.196<.001<.00134
PDACRNY4P24 →+1.389+0.513.003<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration