Eating behavior

Across TCGA cell cohorts, RNA activity of the Eating behavior pathway is significantly associated with the RNA expression of multiple genes, with the LUNG_SCLC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are CPT1A, TMOD2, and VEGFA, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Eating behavior activity versus CPT1A in LUNG_SCLC (Pearson r = 0.57).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CPT1A →	+1.981	+1.169	.004	.005	2	4
LUNG_SCLC	TMOD2 →	-2.245	-1.870	.004	<.001	3	3
KIDNEY	VEGFA →	+3.216	+1.859	.006	<.001	3	3
LUNG_SCLC	UNC5CL →	+1.088	+1.491	<.001	.004	3	3
LUNG_SCLC	MELK →	-1.107	-1.244	<.001	.002	3	3
LUNG_SCLC	PPFIBP2 →	+3.423	+1.673	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0042755 vs CPT1A — LUNG_SCLC

Explore this scatter interactively →