Ovulation cycle

Across TCGA patient cohorts, RNA activity of the Ovulation cycle pathway is significantly associated with the RNA expression of multiple genes, with the OV cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are LOXL1-AS1, MINAR1, and RPL36AP43, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Ovulation cycle activity versus LOXL1-AS1 in OV (Pearson r = 0.20).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LOXL1-AS1 →	+0.477	+0.227	.002	<.001	3	4
LSCC	MINAR1 →	+0.381	+0.176	.003	.002	3	4
CCRCC	RPL36AP43 →	+0.632	+0.290	<.001	.004	3	3
BRCA	TASP1 →	+0.366	+0.277	.002	.004	3	3
GBM	BICC1 →	+0.660	+0.288	.001	.005	3	3
GBM	TRIP10 →	+0.366	+0.318	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0042698 vs LOXL1-AS1 — OV

Explore this scatter interactively →